Biological age based on DNA methylation patterns is a more accurate guide of wellness outcomes than chronological age
When we set out to create TruAge, we asked a simple question: "What if we could read the biological story written in your cells?" The result is a technology that reveals aging patterns invisible to standard testsâproviding insights that can transform how you approach longevity and wellbeing.
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Advanced epigenetic algorithms enable precise quantification of multiple aging dimensions beyond a single biological age number. The pace of aging, not just current biological age, provides critical insights into your aging trajectory. Comprehensive analysis across pace of aging, telomere health, immune function, and mitotic age offers integrated assessment. Your results create a personalised blueprint for targeted longevity interventions across multiple biological dimensions.
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How your lifestyle choices influence gene expression without changing DNAâand why this matters for aging.
Your DNA is like your body's hardwareâit stays relatively unchanged throughout life. But your epigenetic patterns are the softwareâconstantly updating based on how you live.
By examining these patterns, we can see how your experiences, environment, and choices have influenced your cellular functionârevealing not just your current status, but the trajectory of your aging process.
Research in this field continues to explore how methylation patterns relate to biological processes. While chronological age simply counts years lived, methylation patterns may provide additional insights into cellular processes that researchers are studying for their potential relevance to wellbeing.
The epigenome plays a crucial role in numerous physiological processes:
This multi-dimensional approach provides unprecedented insight into your biological aging at the functional level where it may impact recovery and longevity potential.
Our analysis examines foundational methylation sites associated with key aspects of aging.
Pace of Aging+
Pace of aging measures how quickly or slowly your body is biologically agingâessentially the speed at which age-related deterioration is occurring. This dimension focuses not on your current biological age but on your aging trajectory.
Key aspects of this assessment include:
Research shows that pace of aging varies significantly between individuals of the same chronological age, with some people aging as much as 2-3 times faster than others. These differences have profound implications for cognitive function, and longevity potential.
Telomere Health+
Telomere health assessment examines methylation patterns associated with telomere function and cellular replication capacity. While not measuring telomere length directly, this epigenetic approach provides insights into cellular aging processes that influence tissue health and regeneration.
Key components include:
This assessment provides insights into cellular aging processes that influence recovery, regeneration, and overall tissue health throughout the body.
Immune Epigenetics+
This dimension examines methylation patterns that researchers have studied in relation to immune function, with particular focus on sites associated with inflammatory processes.
Key components include:
Research suggests that these methylation patterns may provide more stable information about long-term inflammatory processes than conventional blood tests, which can fluctuate based on recent exposures.
Mitotic Age+
This dimension examines methylation sites that researchers have associated with cellular turnover processes, providing insights into tissue renewal and maintenance.
Key components include:
This dimension helps explore methylation patterns potentially related to tissue renewal, recovery capacity, and cellular maintenance.
Weight Loss Response+
Weight loss response assessment examines epigenetic patterns associated with metabolic efficiency and responsiveness to caloric restriction.
Key components include:
This assessment helps explain why generic weight management approaches may not be equally effective for all individuals, guiding more personalised and effective strategies.
Alcohol Consumption Impact+
This dimension examines methylation sites that researchers have studied in relation to alcohol metabolism and its potential effects on biological processes.
Key components include:
This assessment provides insights into how lifestyle factors may influence methylation patterns, potentially guiding personalized approaches to wellbeing practices.
Fitness Age+
Fitness age assessment examines methylation patterns associated with physical functionality, cardiovascular capacity, and mobility.
Key components include:
This dimension provides insights into physical functionality from an epigenetic perspective, connecting biological aging with real-world physical capacity and performance.
How we transform complex methylation data into actionable metabolic insights.
Our proprietary scoring system synthesises multiple epigenetic indicators into actionable metrics across each module:
Your comprehensive dashboard translates complex epigenetic data into practical understanding:
Our technology allows for analysis at multiple levels of methylation specificity:
Our analysis and interpretation are grounded in peer-reviewed epigenetic research, including:
Our analysis begins with a simple, non-invasive collection process:
Our analysis and interpretation are grounded in peer-reviewed research on epigenetic aging:
Recent research uncovers how epigenetic mechanisms regulate mitochondrial bioenergetics, shaping cellular energy production, aging, and resilience across tissue types. Studies highlight the role of nutrition in influencing the epigenome, revealing integrated pathways through which dietary patterns, methylation dynamics, and cellular programming converge to affect overall health and longevity.
Emerging findings illustrate how lifestyle-related epigenetic modifications influence mitochondrial function, heat shock response, and cellular stress resilience. Multi-omics integration reveals novel biomarkers tied to energy metabolism and longevity, while targeted factors like Klotho protein expression show direct links to protective methylation patterns that promote extended cellular function and lifespan.
Advanced methylation profiling platforms and high-throughput sequencing systems are driving precision health innovations. State-of-the-art arrays and genome-wide mapping technologies enable large-scale epigenetic assessment, while computational tools enhance the integration of complex multi-omics data for predictive health insights. Regulatory-grade components support clinical-grade methylation testing and application.
The TruAge Complete achieves its full potential when combined with our other testing modalities:
Together, these insights provide a complete view of your health landscape, enabling truly personalised approaches to longevity optimisation.
Our platform is designed for continuous advancement:
This test is part of the broader P4Health platformâbuilt on our Predictive, Preventative, Personalised, and Participatory approach. We don't just analyse data; we help you act on it through a connected ecosystem of tracking tools, health journeys, and community-led support.
Our comprehensive epigenetic analysis supports various applications:
Our clinical partnership program provides specialised access to patient management tools, batch testing options, and practitioner resources.
Our enterprise solutions offer scalable testing, analytics dashboards, and group health optimisation programs.
This scientific overview is provided for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. The epigenetic analysis is designed to provide insights about biological patterns that may support general wellness. Our analysis uses TGA-registered technology (ARTG entries 297844 and 398180). Individual results may vary. Always consult with your healthcare professional regarding health concerns or before making significant changes to your health regimen.
